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Currently Enrolling Studies

COPD Study #1
A 28 week, placebo-controlled, add-on therapy for patients with moderate to severe COPD, on dual or triple therapy, that are still experiencing exacerbations, with active symptoms.

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Inclusion Criteria:

  • Must be 40-75 years old
  • Must have diagnosed COPD for at least one year
  • Former smokers

COPD Study #2
A 52 week study for COPD patients comparing new triple therapy vs dual therapy inhalers.

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Inclusion Criteria:

  • Must be 40 or over
  • Symptomatic COPD diagnosed greater than a year ago

MAC/NTM (non-tuberculosis mycobacterium)
This study is for patients with MAC disease to compare 2 vs 3 antibiotic therapy.

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Inclusion Criteria:

  • Be over 18
  • Must have culture positive MAC

Crohn’s Disease (M14-431 and M14-433)
For Crohn’s Disease patients who have had an inadequate response or are intolerant to biologic/conventional therapy.

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Inclusion Criteria:

  • Participants between 18 and 75 years, inclusive
  • Confirmed diagnosis of Crohn’s disease for at least 3 months
  • Failed or intolerant to one or more biologic/conventional agents

Non-Cystic Fibrosis Bronchiectasis
A 52-week placebo-controlled study for patients with non-cystic fibrosis bronchiectasis

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Inclusion Criteria:

  • Must be between 18 and 85 years old
  • Must be symptomatic
  • Have had at least 2 exacerbations in the past 12 months

COPD / Asthma Phone App Study
The purpose of this study is to see if COPD and Asthma patients can benefit from a smartphone application.

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The study tests an at-home decision support application that tracks patients’ symptoms, signs, and medical history and offers guidance when patients are concerned about their health.  The app is free for Apple and Android phones. The app gives on-demand decision support to patients, which may help them to manage their health in a timely and accurate manner.

Pediatric Migraine
Study of an oral medication for kids and adolescents experiencing migraines

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Inclusion Criteria: 

  • Must be 6 to 17 years old
  • Been experiencing migraines for at least 6 months

Ulcerative Colitis
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis.

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The purpose of this study is to evaluate the safety of different doses of ABT-494 and determine how well it works, as well as the pharmacokinetics (PK) (how drug is absorbed, distributed, and eliminated in the body over time) of ABT-494 in subjects with moderate to severe Ulcerative Colitis (UC).  If you have been diagnosed with Ulcerative Colitis and are experiencing symptoms such as bloody diarrhea, abdominal pain and a sudden and constant feeling that you have to move your bowels. Additionally, you are unable to tolerate or you have had insufficient response to treatment with medications that help reduce the inflammation associated with your disease, such as corticosteroids, immunosupressants, and/or biologics, you may be eligible.


Inclusion Criteria:

  • Diagnosis of ulcerative colitis for 90 days or greater prior to Baseline, confirmed by colonoscopy during the Screening Period, with exclusion of current infection, colonic dysplasia and/or malignancy. Appropriate documentation of biopsy results consistent with the diagnosis of UC, in the assessment of the Investigator, must be available.
  • Ages Eligible for Study: 18 Years to 75 Years
  • Demonstrated an inadequate response to, loss of response to, or intolerance to corticosteroids, immunosuppressants, and/or biologic therapies.
  • Female participants of childbearing potential must have a negative serum pregnancy test at the Screening Visit and a negative urine pregnancy test at the Baseline Visit.
  • Male participants must agree to follow protocol-specified pregnancy avoidance measures, including refraining from donating sperm, for up to 90 days post last dose of study drug.

Asthma Observational
An observational study following patients with severe asthma for up to 5 years.

Pediatric pneumococcal vaccine
For healthy infants to determine the efficacy of the vaccine to prevent infection of more strains of pneumococcal

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Inclusion Criteria: 

  • Must be 42 to 98 days old
  • Cannot have previous vaccines other than Hep B at time of birth

Eosinophilic Esophagitis
For adolescents and adults with Eosinophilic Esophagitis

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Inclusion Criteria: 

  • Must be 12-75 years old
  • Must be able to maintain stable diet throughout duration of study

What is the Research Department?

Modern medicine is driven forward through research at every level—biomedical, experimental, clinical, and many others. From tried and true approaches, to new paradigms, medical research touches nearly every component of medicine, and can involve public health, biochemistry, clinical research, microbiology, physiology, oncology, and surgery, plus research into communicable and non-communicable diseases.

About Clinical Trials

A clinical research trial is a partnership and a commitment between doctors and volunteer patients. It is the final test in a series of many carefully controlled scientific studies. We recruit for clinical trials and studies in the following areas:

  • Diabetes – Type I and Type II
  • Rheumatoid arthritis
  • Ulcerative Colitis
  • Pediatric vaccines
  • Follow-up extension studies that ensure the quality and safety
  • Crohn’s Disease

Research Department Staff

Medical Director for Research: Marcia Sparling, MD

Nicole Gentes, MA, CRC
Mattison Martin, BS, CRC
Mary Madura, MA, CRC

Contact Information:
Phone: 360-397-3388
Fax: 360-604-1752
Email: Vancouver Clinic's research department's email address is

Research Providers

Christina L. Orr, MD.

Christina L. Orr, MD

Jason Etzel, MD.

Jason Etzel, MD

Hair coloring - Layered hair

Jennifer Poste, MD


Jessica Lucier, MD


Julie Lawrence, ARNP

Nurse Practitioner

Kathryn (Katy) Thellman, FNP

Nurse Practitioner
Lisa Vasanth, MD.

Lisa Vasanth, MD

Nicholas Wysham, MD.

Nicholas Wysham, MD

Stacey Condren, MD.

Stacey Condren, MD


Research Locations

Vancouver, WA Locations

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87th Avenue Clinic

700 NE 87th Ave
Vancouver, WA 98664


More Info

Information about Research


Making the Decision to Participate

There are two reasons to participate in a clinical research trial: to help yourself and to help others.

It is possible the treatment being tested will improve your health. A new drug or new procedures may reduce pain or perhaps even cure your illness. All clinical research trial patients receive a great deal of personal medical attention.

You may also decide to participate in a clinical research trial for the satisfaction that comes from being a part of scientific research. Many people hope for a breakthrough treatment that will make coping with an illness easier or eliminate it altogether. Clinical research trial volunteers help make those discoveries available to people all across the country and around the world.

Being a volunteer is a serious commitment. Deciding to participate in a clinical research trial means weighing possible benefits against possible risks. You should only make the commitment to participate in a clinical research trial after you have carefully discussed all the facts with your doctor and/or the research study coordinator.


Who conducts clinical research trials?
Pharmaceutical companies, research institutions, or other health organizations sponsor a clinical research trial. Sponsors are responsible for funding and for designing the trial protocol (the set of detailed guidelines that investigators follow in order to conduct the same clinical research trial at different locations). Trained doctors, nurses, and medical researchers conduct the trials.

What is a clinical research trial like?
Participating in a clinical research trial is much like a regular visit to a doctor’s office, but with even greater personal attention. The success of any trial depends on its volunteers. Patients are treated professionally and with care.

What are the risks?
Risks vary from trial to trial. Known risks and discomforts will be explained by the study physician prior to each patient’s participating in the study. In addition to the known risks, there may be unknown risks such as medication side effects. While it is possible that some side effects could be permanent or even life threatening, most are temporary and will go away as soon as the treatment is stopped.

Will I be compensated?
There are no patient charges for medical services rendered to participants of clinical research studies. Medical tests and physician services associated with the study, in addition to the substance, procedure, or device being tested, are provided to participating patients. Some studies also include a stipend paid to participants for their involvement in the project as reimbursement for time and travel. This amount varies, depending on the nature of the study and the patient involvement.

Are there requirements for volunteers?
Each trial has certain requirements (for example: diagnosis, medical condition, and age), and patients must meet these requirements. The physician conducting the study will review each volunteer’s medical history and the study requirements to determine who can participate. Once a patient is enrolled in the trial, there are very specific guidelines which must be followed.

For the eligibility requirements for a particular trial, contact the Research Department at Vancouver Clinic to speak to the coordinator for that study.

What is expected of volunteers?
Volunteers need to be at appointments on time, to follow instructions carefully, to return phone calls from the study coordinator, and especially to take any medication exactly as told. This is needed in order to collect the information necessary for a successful study.

What can volunteers expect from the clinical research trial team?
Prior to enrolling in a trial, volunteers should expect to receive complete information about the trial. They should not participate in any clinical research trial unless their questions have been reasonably answered.

Study procedures, risks and benefits are explained to volunteers during the informed consent process. This is required by law to make sure volunteers understand what is involved in a trial.

Volunteers can also expect complete information about the schedule and duration of the trial, directions to the trial location, and the name of someone to contact with questions or problems.

Are volunteers protected?
As patients under doctor’s supervision, volunteers are protected by the same laws and ethics that normally regulate the medical profession. Informed consent helps protect volunteers by making sure they have been given all the necessary information about a trial. An institutional review board (IRB) reviews the general progress of the trial. The IRB also regulates clinical research trial advertisements to reduce misleading claims.

Can volunteers change their minds after a clinical research trial starts?
Volunteers are always free to change their minds and stop participating in a trial at any time. They should keep in mind, however, that when even a few patients stop participating mid-trial (because of disinterest or other reasons), there may not be enough patients remaining to achieve reliable results.

How do you become a medical researcher?
The field of medical research continues to grow, thanks in part to innovation that leads to new treatments and tools for prevention and health maintenance. There are a number of pathways you can follow for a career in medical research, including certain MD-PhD programs that provide training for students who wish to become research physicians (or physician investigators). Another path involves receiving a PhD in biomedical sciences.

What type of person becomes a medical researcher?
Medical researchers tend to have a keen interest in contributing to the greater body of medial knowledge available to professionals for the sake of their patients. Medical researchers must possess a sharp intellect, in addition to the emotional strength it takes to complete an advanced degree. The best researchers also possess strong communications skills, which helps them draft grant proposals and communicate their findings.

What’s driving the growth of medical research as a career?
Many people point to the simple fact that we’re living longer as to why medical research, as a field, continues to grow. Here’s another thing to consider: humans have been trying to make ourselves better for as long as we’ve been getting sick. In that way, medical research goes back to the beginning of time. In the first half of the 20th century, it led to countless breakthroughs—vaccines for measles and polio; insulin treatment for diabetes; antibiotics that any number of illnesses. More recently, medical research has improved HIV/AIDS treatments, has spurred new surgical techniques such as microsurgery, and has forged successful treatments for types of cancer that, a quarter century ago, were almost always fatal. As challenges remain, medical researchers continue to step forward and meet them head-on.

Questions to ask your doctor before participating in a clinical research trial:

  • What is the purpose of the trial?
  • What treatments will be done and how?
  • How will patient safety be checked?
  • What are the possible side effects and risks of this treatment?
  • How could this treatment benefit me?
  • What treatments, other than the one being tested, are available for the same condition?
  • How will the trial affect my daily life?
  • How long will the trial last?
  • Who is sponsoring the trial?
  • Will I have to pay for anything?
  • What happens if I am harmed by the trial?
  • Will I be able to stay on this treatment when the trial is over?
Sponsor Info

Our Facilities
Vancouver Clinic is the largest multi-specialty group practice in Vancouver, Washington. There are 300+ physicians and mid-level providers in five locations in Clark County. Vancouver is located along the Columbia River adjacent to the Portland, Oregon metropolitan area and 12 miles from the Portland International Airport.

Diagnostic services include fully accredited laboratory, full imaging services (diagnostic radiology, mammography, ultrasound, CT, MRI, bone densitometry (DEXA)), ECG and monitoring services, an infusion center, pulmonary function lab, cardiac testing (treadmill, Holter, nuclear studies), Ambulatory Surgery Center and a 10-bed Sleep Center.

Patient Demographics
The population of Clark County is approximately 400,000. The Clinic’s active patient population (seen in the last 2 years) is roughly 125,000 patients.

Hospital Affiliations
Physicians at Vancouver Clinic are affiliated with PeaceHealth Southwest Medical Center, located four blocks from the main Clinic campus. Many physicians are also affiliated with Legacy Salmon Creek Hospital, located approximately 8 miles from the main Clinic campus.

Industry Services
Secure and controlled building access and patient areas
Secure, climate-controlled drug storage
Patient management database and electronic medical record
Excellent FDA audit record
We utilize central IRBs
-20 C freezer
Refrigerated centrifuge

Research Department Staff
Medical Director for Research: Marcia Sparling, MD

Nicole Gentes, MA, CRC
Mattison Martin, BS, CRC
Mary Madura, MA, CRC
Kirk Raboin

Contact Information:
Phone: 360-397-3388
Fax: 360-604-1752

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